29 C
Colombo
Tuesday, October 4, 2022

Antibody responses decline, T cell responses remain 12 weeks after Sinopharm second dose

- Advertisement -

Antibody responses declined in all age groups, specially in those who are more than 60 years after 12 weeks from Shinopharm second dose, while T cell responses persisted, said Prof. Neelika Malavige, Head, Department of Immunology and Molecular Medicine of University of Sri Jayewardenepura.

The Sinopharm is an inactivated COVID-19 vaccine, which is currently given emergency use authorization by the WHO and is the main vaccine used in many Asian and Middle East Countries. A new study was carried out to determine the kinetics and persistence of immune responses following the Sinopharm/BBIBP-CorV, by investigating the immune responses in a cohort of Sri Lankan individuals.

USJ researchers including Prof. Neelika Malavige and Dr. Chandima Jeewandara from Allergy Immunology and Cell Biology Unit, Department of Immunology and Molecular Medicine have been studying immune responses to different types of COVID-19 vaccines used in Sri Lanka.

Results of the current research show that while the SARS-CoV-2 specific total antibodies, and sspecially neutralizing antibodies and antibodies to the receptor binding domain significantly declined, the memory T cell and B cell responses persisted.

“Since the ACE2 receptor blocking antibodies (neutralizing antibodies that associate with protection) was shown to significantly decline in all age groups and especially in the elderly, it is important to carry out long term efficacy studies to assess the waning of immunity on hospitalization and severe disease in order to decide on booster doses in different populations.” said Prof. Malavige.

RECENT ARTICLES - SINHALA

කෝප් කමිටුවෙන් හර්ෂ ඉල්ලා අස්වෙයි

තමන් කෝප් කමිටුවෙන් ඉල්ලා අස්වන බවට සමගි ජනබලවේගය පක්ෂයේ පාර්ලිමේන්තු මන්ත්‍රී හර්ෂ ද සිල්වා මහතා පවසනවා. ට්විටර් පණිවුඩයක් නිකුත්...

Breaking: සුදේව හෙට්ටිආරච්චි ස්වර්ණවාහිනියෙන් ඉල්ලා අස්වෙයි

0
ස්වර්ණවාහිනී නාලිකාවේ විධායක අධ්‍යක්ෂ්‍යවරයා ලෙස කටයුතු කළ සුදේව හෙට්ටිආරච්චි මහතා එම තනතුරින් ඉල්ලා අස්වී තිබෙනවා. ඒ අනුව සිය ඉල්ලා...

අත්‍යාවශ්‍ය සේවා නම් කරමින් රනිල්ගෙන් තවත් ගැසට්ටුවක්

සාමාන්‍ය ජන ජීවිතය පවත්වාගෙන යාම සඳහා අත්‍යවශ්‍ය වන බවට හඳුනාගත් සේවාවන් කිහිපයක් හඳුනාගනිමින් ඒවා සඳහා අතිවිශේෂ ගැසට්ටුවක් නිකුත් වී තිබෙනවා.

RECENT ARTICLES - ENGLISH

Tom Moody and Sri Lanka Cricket to part ways

0
Former Sri Lankan Head Coach Tom Moody, who joined Sri Lanka Cricket once again last year as the director of cricket for...

Temples to switch off lights on Poya Day to protest tariff hike?

0
A proposal has been presented to the Central Province Maha Sangha Sabha to turn off the lights within all temples across the...

Horrific details about captivity of 7 Sri Lankans by Russian soldiers revealed

0
A Ukrainian journalist and the Kharkiv region’s police have disclosed appalling details about the torture the seven Sri Lankans endured while they...